This gene encodes a serine/threonine-protein kinase that functions in cell division. Together with the kinesin KIF14, this protein localizes to the central spindle and midbody, and functions to promote efficient cytokinesis. This protein is involved in central nervous system development. Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011].
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Protein Aliases: citron (rho-interacting, serine/threonine kinase 21); citron kinase; Citron Rho-interacting kinase; citron-N; CRIK; CTRO; KIAA0949; Rho-interacting; Rho-interacting, serine/threonine-protein kinase 21; serine/threonine kinase 21; Serine/threonine-protein kinase 21; STK21
Gene Aliases: C030025P15Rik; CIT; Cit-k; CRIK; CRIK-SK; KIAA0949; STK21