The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed at high levels throughout spermatogenesis and in mature sperm. It binds the RI and RII subunits of PKA in testis. It may serve a function in cell cycle control of both somatic cells and germ cells in addition to its putative role in spermatogenesis and sperm function. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: A kinase (PRKA) anchor protein 11; a kinase anchor protein 220 kDa; A-kinase anchor protein 11; A-kinase anchor protein 220 kDa; A-kinase anchoring protein, 220kDa; AKAP 220; AKAP-11; PRKA11; protein kinase A anchoring protein 11; Protein kinase A-anchoring protein 11; protein phosphatase 1, regulatory subunit 44
Gene Aliases: AKAP-11; AKAP11; AKAP220; KIAA0629; PPP1R44; PRKA11
UniProt ID: (Human) Q9UKA4
Entrez Gene ID: (Human) 11215