Peptide sequence: LTNSRSVLQQ LTPMNKTEVV HKHSRLAEVL QLGSDILPQY KQEAPKTPPH
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. The KCNH5 gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. KCNH5 is not expressed in differentiating myoblasts.
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Protein Aliases: Eag2; Ether-a-go-go potassium channel 2; ether-a-go-go-related potassium channel 2; hEAG2; potassium channel, voltage gated eag related subfamily H, member 5; Potassium voltage-gated channel subfamily H member 5; potassium voltage-gated channel, subfamily H (eag-related), member 5; rEAG2; Voltage-gated potassium channel subunit Kv10.2
Gene Aliases: BOS_11160; EAG2; H-EAG2; hEAG2; KCNH5; Kv10.2