Peptide sequence: ADFYQIRPLL DALRELEASQ GTPAPTAALL HADVDVSPRL VHFSARRGPH
Sequence homology: Human: 100%; Mouse: 90%
The KCTD11 gene encodes a protein that has been identified as a suppressor of Hedgehog signaling. Its inactivation might lead to a deregulation of the tumor-promoting Hedgehog pathway in medulloblastoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BTB/POZ domain-containing protein KCTD11; KCASH1 protein; potassium channel tetramerisation domain containing 11; Potassium channel tetramerization domain-containing protein 11; retinoic acid, EGF, and NGF upregulated; retinoic acid, EGF, NGF induced gene protein; retinoic acid, EGF, NGF induced gene/potassium channel tetramerization domain containing 11; RING-type E3 ubiquitin transferase subunit KCTD11
Gene Aliases: AF465352; C17orf36; KCASH1; KCTD11; REN; REN/KCTD11
Molecular Function: enzyme modulator