Peptide sequence: MARTVVLITG CSSGIGLHLA VRLASDPSQS FKVYATLRDL KTQGRLWEAA
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 91%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
HSD17B1 is favors the reduction of estrogens and androgens. It also has 20-alpha-HSD activity. It uses preferentially NADH.
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Protein Aliases: 17-beta-dehydrogenase 1; 17-beta-HSD 1; 17-beta-hydroxysteroid dehydrogenase type 1; 17beta-hydroxysteroid dehydrogenase type 1; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; E2DH; Estradiol 17-beta-dehydrogenase 1; estradiol 17-beta-dehydrogenase-1; hydroxysteroid (17-beta) dehydrogenase 1; hydroxysteroid (17-beta) dehydrogenase 1 isoform; Hydroxysteroid dehydrogenase 17 beta, type 1; Placental 17-beta-hydroxysteroid dehydrogenase; Short chain dehydrogenase/reductase family 28C member 1; short chain dehydrogenase/reductase family 28CE, member 1
Gene Aliases: 17beta-HSD; 17BHD1; 17HSDB1; BOS_19074; E17KSR; E2DH; EDH17B1; EDH17B2; EDHB17; HSD17; HSD17B1; Hsd17ba; SDR28C1