In Western blots, approximately 25% cross-reactivity with recombinant human ACE and 5% cross-reactivity with recombinant human ACE-2 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.
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Protein Aliases: ACE; ACE1; Angiotensin-converting enzyme; Angiotensin-converting enzyme, soluble form; CD143; DCP; DCP1; Dipeptidyl carboxypeptidase I; dipeptidyl peptidase; Kininase II; MGC26566; MVCD3
Gene Aliases: Ace; AW208573; CD143; Dcp1
UniProt ID: (Mouse) P09470
Entrez Gene ID: (Mouse) 11421