Reconstitute at 0.2 mg/mL in sterile PBS.
This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4, 5-bisphosphate to generate the second messengers diacylglycerol and inositol 1, 4, 5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3; Phosphoinositide phospholipase C-delta-3; phospholipase C, delta 3; Phospholipase C-delta-3; PLC delta3; PLC-delta-3
Gene Aliases: 2610205J15Rik; KIAA1964; mKIAA1964; PLC-delta-3; PLCD3