Immunogen sequence: LRVLEKDAEV IVDWRPLDDA LDSSSILYAR KDSSSVVEWT QAPKERGHRG SEHLNSYEAE WDMVNTVSFK RKPHTNGDAP SHRNGKSKWS FLFSLTDLKS IKQNKEGMGW SYLVFCLKDD VVLPALHF
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 94%.
Acts as a regulator of transcriptional activation. Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GAP for RAB7; GTPase-activating protein RAB7; TBC1 domain family member 15; TBC1 domain family, member 15; Tre-2-budding uninhibited by benzimidazole-cell division cycle 16 domain, domain family member 15; Tre2/Bub2/Cdc16 domain family member 15
Gene Aliases: RAB7-GAP; TBC1D15
UniProt ID: (Human) Q8TC07
Entrez Gene ID: (Human) 64786
Molecular Function: GTPase-activating protein