This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: ATDSRTPEVP AGEGPRRGLG APLTEDQQNR LSEEIEKKWQ ELEKLPLREN KRVPLTALLN QSRGERRGPP SDGHEALEKE VQALRAQLEA WRLQGEAPQS A\r
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 85%.
This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Protein Tara; tara-like protein; TRIO and F-actin-binding protein; Trio-associated repeat on actin
Gene Aliases: AI428493; DFNB28; dJ37E16.4; EST478828; HRIHFB2122; KIAA1662; mKIAA1662; TAP68; TARA; TRIOBP