Immunogen sequence: VRKITLSRAV RTMQNLFPEE YNFYPRSWIL PDEFQLFVAQ VQMVKDDDPS WKPTFIVKPD GGCQGDGIYL IKDPSDIRLA GTLQSRPAVV QEY
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 86%.
TTLL11 is a polyglutamase which preferentially modifies alpha-tubulin. It is involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step. TTLL11 is required for CCSAP localization to both spindle and cilia microtubules.
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Protein Aliases: bA244O19.1; C9orf20; Tubulin polyglutamylase TTLL11; tubulin tyrosine ligase like11; tubulin tyrosine ligase-like family member 11; tubulin tyrosine ligase-like family, member 11; Tubulin--tyrosine ligase-like protein 11
Gene Aliases: bA244O19.1; C9orf20; TTLL11
UniProt ID: (Human) F8W6M1
Entrez Gene ID: (Human) 158135