Immunogen sequence: MFWKFDLNTT SHVDKLLDKE HVTLQELMDE DDILQECKAQ NQKLLDFLCR QQCMEELVSL ITQDPPLDME EKVRFKYPNT ACELLTCDVP QISDRLGGDE SLLSLLYDFL DHEPPLNPLL ASFFS\r
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 74%.
Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6- mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: protein phosphatase 6, regulatory subunit 2; SAPS domain family member 2; SAPS domain family, member 2; Serine/threonine-protein phosphatase 6 regulatory subunit 2
Gene Aliases: KIAA0685; PP6R2; PPP6R2; SAP190; SAPS2
UniProt ID: (Human) O75170
Entrez Gene ID: (Human) 9701