Immunogen sequence: MADSSYNLEV QNILSFLKMQ HLNPDPQLIP EQITTDITPE CLVSPRYLKK YKNKQITARI LEA
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 97%.
This gene encodes a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain. The protein is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in MYH9 are the cause of non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.
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Protein Aliases: Fermitin family homolog 2; kindlin 2; Kindlin-2; MIG-2; mitogen inducible gene 2 protein; Mitogen-inducible gene 2 protein; PH domain-containing family C member 1; pleckstrin homology domain containing, family C (with FERM domain) member 1; pleckstrin homology domain containing, family C member 1; Pleckstrin homology domain-containing family C member 1
Gene Aliases: FERMT2; KIND2; mig-2; MIG2; PLEKHC1; UNC112; UNC112B
UniProt ID: (Human) Q96AC1
Entrez Gene ID: (Human) 10979