Immunogen sequence: RIKSCKISVK EEHGCLPNSK KKEHRKFYTI HCTGYLRSWP PNIVGMEEER NSKKD
Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 64%.
ARNTL2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription. Also, in umbilical vein endothelial cells, ARNTL2 activates SERPINE1 through E-box sites. This transactivation is inhibited by PER2 and CRY1.
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Protein Aliases: aryl hydrocarbon receptor nuclear translocator-like 2; Aryl hydrocarbon receptor nuclear translocator-like protein 2; Basic-helix-loop-helix-PAS protein MOP9; bHLHe6; BMAL2; Brain and muscle ARNT-like 2; Class E basic helix-loop-helix protein 6; CLIF; CYCLE-like factor; Member of PAS protein 9; MGC149671; MGC149672; MOP9; PAS domain-containing protein 9; PASD9; transcription factor BMAL2
Gene Aliases: ARNTL2; BHLHE6; BMAL2; CLIF; MOP9; PASD9
UniProt ID: (Human) Q8WYA1
Entrez Gene ID: (Human) 56938