Immunogen sequence: MILLQHAVLPP PKQPSPSPPM SVATRSTGTL QLPPQKPFGQ EASLPLAGEE ELSKGGEQDC ALEELCKP
Highest antigen sequence identity to the following orthologs - mouse 78%, rat 80%.
This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid.
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Protein Aliases: matrin type 3; p53 target zinc finger protein; p53-activated gene 608 protein; PAG608; WIG-1; WIG-1/PAG608 protein; WIG1; zinc finger; Zinc finger matrin-type protein 3; Zinc finger protein WIG-1; zinc finger protein WIG1
Gene Aliases: PAG608; WIG-1; WIG1; ZMAT3
UniProt ID: (Human) Q9HA38
Entrez Gene ID: (Human) 64393