Immunogen sequence: DVKRTVDLSSH LAKVTAEVVL AHLGGGSTSR ATSFLLALEP ELEARLAHLG VQVKGEDEEE NNLEVRETKI KGKSGRFFTV KLPVALDPGA KISVIVETVY THVLHPYPTQ ITQSEKQFVV FEGNHYFYSP YPTKTQ
Highest antigen sequence identity to the following orthologs - mouse 93%, rat 93%.
Ribophorins 1 and 2 are abundant and highly conserved glycoproteins residing in the endoplasic reticulum, that participate in ribosome binding. Mammalian oligosaccharyltransferase activity is associated with a protein complex composed of RPN1, RPN2, and an oligosaccharyltransferase protein. RPN1 is a component of the proteasome base. The ubiquitin-like (UBL) domain of recombinant Rad23 interacts with proteasomes through the leucine-rich repeat domain of RPN1. The RPN1 gene maps to chromosome 3 in somatic cell hybrids, and the RPN2 gene maps to chromosome 20 by in situ hybridization.
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Protein Aliases: Dolichyl-diphosphooligosaccharide--protein; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; dolichyl-diphosphooligosaccharide-protein glycosyltransferase 67 kDa subunit; oligosaccharyltransfe; oligosaccharyltransferase 1 homolog; oligosaccharyltransferase complex subunit (non-catalytic); Ribophorin I; Ribophorin-1; RPN-I
Gene Aliases: OST1; RBPH1; RPN1
UniProt ID: (Human) P04843
Entrez Gene ID: (Human) 6184