Immunogen sequence: GLFSHQTWEQI SSDLTRFQDS MVNSF
Highest antigen sequence identity to the following orthologs - mouse 38%, rat 38%.
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger protein 225 (ZNF225) is a 706 amino acid member of the Krueppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZNF225 contains eighteen C2H2-type zinc fingers and one KRAB domain through which it is thought to be involved in DNA-binding and transcriptional regulation.
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Protein Aliases: Zinc finger protein 225; ZN225
Gene Aliases: ZNF225
UniProt ID: (Human) Q9UK10
Entrez Gene ID: (Human) 7768