Immunogen sequence: EPKEKGQLYNL PAEIPCPTLT PPTPPSHGPT PGNIFFLETS DRTNPNFLFM CSVESAARTH PESHVLVLMK GLPGGNASLP RHLGISLLSC FPNVQMLPLD
Highest antigen sequence identity to the following orthologs - mouse 64%, rat 66%.
The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. The encoded protein, which is a type II membrane protein found in the Golgi, is also required for the synthesis of the bacterial verotoxins receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 4-N-acetylglucosaminyltransferase; A14GALT; A4GALT1; alpha 14-galactosyltransferase; alpha-1; Alpha-1,4-galactosyltransferase; Alpha-1,4-N-acetylglucosaminyltransferase; Alpha4Gal-T1; CD77 synthase; GB3 synthase; Gb3S; Globotriaosylceramide synthase; lac; Lactosylceramide 4-alpha-galactosyltransferase; P blood group (P one antigen); P(k); P(k) antigen synthase; P1/Pk synthase; truncated alpha 1,4-galactosyltransferase; UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase
Gene Aliases: A14GALT; A4GALT; A4GALT1; Gb3S; P(k); P1; P1PK; PK
UniProt ID: (Human) Q9NPC4
Entrez Gene ID: (Human) 53947