Predicted to react with Mouse and Rat samples.
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.
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Protein Aliases: T2R31; T2R44; T2R53; Taste receptor type 2 member 31; Taste receptor type 2 member 44; Taste receptor type 2 member 53; taste receptor, type 2, member 31; taste receptor, type 2, member 44
Gene Aliases: T2R31; T2R44; T2R53; TAS2R31; TAS2R44
UniProt ID: (Human) P59538
Entrez Gene ID: (Human) 259290