Predicted to react with Mouse samples.
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex.
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Protein Aliases: Hair keratin K2.10; Hair keratin K2.11; Hair keratin K2.12; hard keratin, type II, 3; hard keratin, type II, 5; hard keratin, type II, 6; hHb3; K83; K85; K86; keratin 83, type II; keratin 85, type II; keratin 86, type II; keratin complex 2, basic, gene 10; keratin complex 2, basic, gene 18; keratin protein HB6; keratin type II; keratin, hair, basic, 3; keratin, hair, basic, 5; keratin, hair, basic, 6 (monilethrix); Keratin, type II cuticular Hb3; Keratin, type II cuticular Hb5; Keratin, type II cuticular Hb6; Keratin-83; Keratin-85; Keratin-86; KRTHB3; type II hair keratin; Type II hair keratin Hb3; Type II hair keratin Hb5; Type II hair keratin Hb6; Type-II keratin Kb23; Type-II keratin Kb25; Type-II keratin Kb26
Gene Aliases: 5430421N21Rik; AA589597; AI325212; BB007925; ECTD4; Hb-3; Hb-5; Hb1; HB3; HB5; HB6; hHb5; K85; K86; Khb4; Krt2-10; Krt2-11; Krt2-18; KRT83; KRT85; KRT86; KRTHB1; KRTHB3; KRTHB5; KRTHB6; MHb4; MNX