CT47 (cancer/testis antigen family 47) is a 288 amino acid protein that is strongly expressed in testis and lowly expressed in placenta and in brain. The gene encoding CT47 is located on human chromosome X, which consists of about 153 million base pairs and nearly 1,000 genes. The combination of an X and Y chromosome lead to normal male development while two copies of X lead to normal female development. There are a number of conditions related to an unsual number and combination of sex chromosomes being inherited. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia, and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently as males carry a single X chromosome.
Protein Aliases: Cancer/testis antigen 47; Cancer/testis antigen 47A; cancer/testis CT47 family, member 1; CT47; CT47A
Gene Aliases: CT47.1; CT47.10; CT47.11; CT47.12; CT47.2; CT47.3; CT47.4; CT47.5; CT47.6; CT47.7; CT47.8; CT47.9; CT47A1; CT47A10; CT47A11; CT47A12; CT47A2; CT47A3; CT47A4; CT47A5; CT47A6; CT47A7; CT47A8; CT47A9
UniProt ID: (Human) Q5JQC4
Entrez Gene ID: (Human) 728096