This target displays homology in the following species: Cow: 86%; Dog: 92%; Guinea Pig: 92%; Horse: 92%; Human: 100%; Mouse: 79%; Pig: 93%; Rabbit: 92%; Rat: 92%
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules.
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Protein Aliases: ATPase class V type 10D; ATPase, class V, type 10D; P4-ATPase flippase complex alpha subunit ATP10D; Probable phospholipid-transporting ATPase VD; putative type IV aminophospholipid transporting ATPase; type IV aminophospholipid transporting ATPase
Gene Aliases: 9830145H18Rik; ATP10D; ATPVD; BOS_6627; D5Buc24e; KIAA1487