The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Armus; BC1D2; likely ortholog of H. sapiens TBC1 domain family, member 2 (TBC1D2); PARIS-1; Prostate antigen recognized and identified by SEREX 1; TBC1 domain family member 2A; TBC1 domain family, member 2; TBC1 domain family, member 2A
Gene Aliases: A630005A06Rik; BC022630; Gm1037; PARIS-1; PARIS1; PP8997; TBC1D2; TBC1D2A