The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
CES2 is a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance.
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Protein Aliases: ACH M1; Acylcarnitine hydrolase; acylcarnitine hydrolase M1; Carboxylesterase 2; carboxylesterase 2 (intestine, liver); carboxylesterase 2E; carboxylesterase 5; carboxylesterase ML3; CE-2; CES 2; CES-2; Cocaine esterase; hCE-2; intestinal carboxylesterase; liver carboxylesterase-2; Methylumbelliferyl-acetate deacetylase 2; P iCE; Peroxisome proliferator-inducible acylcarnitine hydrolase; Pyrethroid hydrolase Ces2e
Gene Aliases: 9030624L02Rik; ACH M1; CE-2; CES 2; CES2; CES2A1; ces2A3; Ces2c; Ces2e; Ces5; ICE; PCE-2