Positive Control: Synthetic peptide: 1:8000
Predicted Reactivity: Mouse (100%), Rat (100%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
BEX1/BEX2 belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. BEX1/BEX2 has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BEX1; BEX2; brain expressed X-linked 2; brain expressed, X-linked 1; Brain-expressed X-linked protein 1; Brain-expressed X-linked protein 2; DJ79P11.1; hBex2; ovarian granulosa cell 13.0 kDa protein hGR74; Protein BEX1; Protein BEX2
Gene Aliases: BEX1; BEX2; DJ79P11.1; HBEX2; HGR74-h