This antibody has specificity for Human LRRC8D.
Component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. It is unclear whether LRRC8D constitutes a pore-forming subunit or whether it is closely associated with the pore.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: leucine rich repeat containing 5; leucine rich repeat containing 8 family; leucine rich repeat containing 8 family, member D; leucine-rich repeat containing 8 family member D; leucine-rich repeat-containing 5; Leucine-rich repeat-containing protein 5; Leucine-rich repeat-containing protein 8D; Volume-regulated anion channel subunit LRRC8D
Gene Aliases: LRRC5; LRRC8D; UNQ213/PRO239
UniProt ID: (Human) Q7L1W4
Entrez Gene ID: (Human) 55144