Immunogen sequence: YDGKDYNPLL ARQGQDVAPP PNPGDQIFNK SKKLIGTAVP QRTSPTGPKN MQTSGRLSNV APPCILRKNP PSARNGGHET DAQILELNQQ LVDLKLTVDG LEKERDFYFS KLR
EB3 is a 282 amino acid homologue of EB1, a protein known to bind APC (adenomatous polyposis coli). It has been shown to bind to tubulin in vitro and microtubules in vivo. Northern blotting shows expressions to be mainly in brain, and to a lesser degree in muscle. EB3 interacts with APCL, a homologue of the tumor suppressor APC, and this interaction may be involved in the stabilization or extension of microtubules.
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Protein Aliases: APC binding protein; EB1 protein family member 3; EB3; EBF3; End-binding protein 3; Microtubule-associated protein RP/EB family member 3; microtubule-associated protein, RP/EB family, member 3; RP3
Gene Aliases: EB3; EBF3; EBF3-S; MAPRE3; RP3
UniProt ID: (Human) Q9UPY8
Entrez Gene ID: (Human) 22924