Keep as concentrated solution.
Positive Control: 293T, A431, HeLa, HepG2, Neuro 2A, C8D30.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
GFM2 is involved in mitochondrial translation, which is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. In Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. This gene encodes one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in at least three transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EF-G2mt; EF-G2mt antibody; EFG2 antibody; elongation factor G 2; Elongation factor G 2, mitochondrial; Elongation factor G2; G elongation factor; G elongation factor, mitochondrial 2; GFM2; GFM2 antibody; hEFG2; hEFG2 antibody; mEF-G 2; mEF-G 2 antibody; mitochondrial 2 antibody; mitochondrial antibody; mitochondrial elongation factor G2; mitochondrial elongation factor G2 antibody; mitochondrial ribosome recycling factor 2; mitochondrial ribosome recycling factor 2 antibody; MRRF2 antibody; MST027 antibody; MSTP027 antibody; ribosome-releasing factor 2; Ribosome-releasing factor 2, mitochondrial; RRF2 antibody; RRF2mt; RRF2mt antibody
Gene Aliases: 6530419G12Rik; A930009M04Rik; EF-G2mt; EFG2; GFM2; hEFG2; mEF-G 2; MRRF2; MST027; MSTP027; RRF2; RRF2mt