Immunogen sequence: MTTYLEFIQQ NEERDGVRFS WNVWPSSRLE ATRMVVPVAA LFTPLKERPD LPPIQYEPVL CSRTTCRAVL NPLCQVDYRA KLWACNFCYQ RNQFPPSYAG ISELNQPAEL LPQFSSIEYV VLRGPQMPLI FLYVVDTCME DEDLQALKES; Positive Samples: B-cell, LO2, HeLa, SGC-7901, HT-29, Mouse brain, Mouse liver, Rat brain; Cellular Location: Golgi apparatus membrane, Peripheral membrane protein, Smooth endoplasmic reticulum membrane
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking.
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Protein Aliases: hSec23A; Protein transport protein Sec23A; Sec23 homolog A, COPII coat complex component; SEC23-related protein A; SEC23A
Gene Aliases: CLSD; Msec23; Sec23; SEC23A; Sec23r