Immunogen sequence: QVDLPMGGVK ALTIDHLAVN DVMLESLRGE GQGLVCDLCN DREVEKRCQT CKANLCHFCC QAHRRQKKTT YHTMVDLKDL KGYSRIGKPI LCPVHPAEEL RLFCEFCDRP VCQDCVVGEH REHPCDFTSN VIHKHGDSVW ELLKGTQPHV EALEEALAQI HIINSALQKR VEAVAADVRT FSEGYIKAIE EHRDKLLKQL EDIRAQKENS LQLQKAQLEQ LLADMRTGVE FTEHLLTSGS DLEILITKRV VVERLRKLNK VQYSTRPGVN DKIRFCPQEK AGQCRGYEIY DLHRAREKQT A; Positive Samples: BxPC-3, 293T, HeLa, Mouse brain, Mouse pancreas; Cellular Location: Cytoplasm, Nucleus
TRIM45 is a member of the tripartite motif family. It may function as a transcriptional repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been described. TRIM45 belongs to a family of tripartite motif (TRIM) proteins that play important roles in a variety of cellular functions, including cell proliferation, differentiation, development, oncogenesis, and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ13181; RING finger protein 99; tripartite motif-containing 45; Tripartite motif-containing protein 45
Gene Aliases: 4921530N01Rik; RNF99; TRIM45