Immunogen sequence: MAMQAAKRAN IRLPPEVNRI LYIRNLPYKI TAEEMYDIFG KYGPIRQIRV GNTPETRGTA YVVYEDIFDA KNACDHLSGF NVCNRYLVVL YYNANRAFQK MDTKKKEEQL KLLKEKYGIN TDPPK; Positive Samples: K-562, HeLa, Mouse spleen; Cellular Location: Nucleus
SF3B14 encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.
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Protein Aliases: pre mRNA branch site protein p14; Pre-mRNA branch site protein p14; SF3B 14 kDa subunit; SF3B14a; spliceosome-associated protein, 14 kDa subunit; Spliceosome-associated protein, 14-kDa; Splicing factor 3B subunit 6; splicing factor 3B, 14 kDa subunit; Splicing factor 3b, subunit 6, 14kDa
Gene Aliases: 0610009D07Rik; 6030419K15Rik; AV001342; CGI-110; HSPC175; HT006; P14; SAP14; SAP14a; SF3B14; SF3B14A; SF3B6