Immunogen sequence: EDSDTRCAAR VMARPRFGAP HASESCSKNG PERGGQDGKA SLEAHRDAPG AGAPPAPGKK EAPPVEGDSE GAMWTAVFDE PANSTPTAPG VVRDVGSSVW AAGTSAPEEK GWAKFTDFQP FCCSESGPRC SSPVDTECSH AEGSRSQGPE KAFSPASPCA WNVCVTRKAP LLASDSSSSG GSHSEDGDQK AASAMDAVSR GPGREAPPLP TVARTEEAVG RVGCADSRLL SPACPAPKEV TAAPAVAVPP EATVAITTAL SKAGPAIPTP AVSSALAVAV PLGPIMAVTA APAMVATLGT VTKDGKTDAP PEGAALNGPV; Positive Samples: HepG2, 293T, Jurkat; Cellular Location: Cytoplasm
Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6- mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.
Protein Aliases: protein phosphatase 6, regulatory subunit 2; SAPS domain family member 2; SAPS domain family, member 2; Serine/threonine-protein phosphatase 6 regulatory subunit 2
Gene Aliases: KIAA0685; PP6R2; PPP6R2; SAP190; SAPS2
UniProt ID: (Human) O75170
Entrez Gene ID: (Human) 9701