Immunogen sequence: ALISCLTGPT KRSTLAPGLL WWDLARQTAS VAPKEEVAIL DDNLVKGPEE LPTGNKKPPG FLPTNEDRLF FLGQKELEGA GSWTPCVGHD GGRDQQETNL; Positive Samples: Mouse testis; Cellular Location: Membrane, Multi-pass membrane protein
Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells. It is a membrane bound glycoprotein with 13 membrane spanning domains and 14 extramembranous domains. It may represent an autoantigen in thyroid.
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Protein Aliases: Na(+)/I(-) cotransporter; Na(+)/I(-) symporter; Na(+)/I(-)-symporter; Na+/I- symporter; Sodium-iodide symporter; Sodium/iodide cotransporter; solute carrier family 5 (sodium iodide symporter), member 5; solute carrier family 5 (sodium/iodide cotransporter), member 5; Solute carrier family 5 member 5; solute carrier family 5, member 5
Gene Aliases: NIS; SLC5A5; TDH1