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Despite the predicted molecular weight, ORAI1 often migrates at a higher molecular weight in SDS-PAGE. A suggested positive control is human ovary tissue lysate.
PA5-20402 can be used with blocking peptide PEP-0519.
ORAI1 is a plasma membrane protein essential for store-operated calcium entry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: calcium release-activated calcium channel 1; Calcium release-activated calcium channel protein 1; calcium release-activated calcium modulator 1; FLJ14466; Protein orai-1; Transmembrane protein 142A
Gene Aliases: CRACM1; D730049H07Rik; IMD9; orai-1; ORAI1; ORAT1; TAM2; TMEM142A
UniProt ID: (Human) Q96D31, (Mouse) Q8BWG9
Entrez Gene ID: (Human) 84876, (Mouse) 109305
Molecular Function: ion channel transporter
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