Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: AVRNDEELNK LLGGVTIAQG GVLPNI
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: H2A-clustered histone 21; histone 2, H2ab; Histone H2A type 2-B
Gene Aliases: H2AB; H2AC21; HIST2H2AB
UniProt ID: (Human) Q8IUE6
Entrez Gene ID: (Human) 317772
Molecular Function: histone
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