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Immunogen sequence: KLKQTTSALEK KMAGRQGREE LIKKGLLEMM EQDAESKTCN PDGGPRSVQS EPPTPKSETL TSEDAQPGS
Highest antigen sequence identity to the following orthologs - mouse 79%, rat 67%.
The protein encoded by this gene is associated with the nuclear scaffold in proliferating cells. It was found to bind to the catalytic subunit of protein phosphatase-1 (PP1) and inhibit PP1 activity, suggesting that this protein may function as a regulatory subunit of PP1. Alternative splicing at this locus results in several transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Phosphatase and actin regulator 3; protein phosphatase 1, regulatory subunit 123; Scaffold-associated PP1-inhibiting protein; Scapinin
Gene Aliases: C20orf101; H17739; PHACTR3; PPP1R123; SCAPIN1; SCAPININ
UniProt ID: (Human) Q96KR7
Entrez Gene ID: (Human) 116154
Molecular Function: phosphatase modulator
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