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ADCYAP1 is adenylate cyclase activating polypeptide 1. Mediated by adenylate cyclase activating polypeptide 1 receptors, this polypeptide stimulates adenylate cyclase and subsequently increases the cAMP level in target cells. Adenylate cyclase activating polypeptide 1 is not only a hypophysiotropic hormone, but also functions as a neurotransmitter and neuromodulator. In addition, it plays a role in paracrine and autocrine regulation of certain types of cells. This gene encodes three different mature peptides, including two isotypes, a shorter form and a longer form.
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Protein Aliases: adenylate cyclase activating polypeptide 1 (pituitary); HSPC190; MGC126852; OTTHUMP00000162201; PACAP; pacap 38; PACAP-27; PACAP-38; PACAP-related peptide; pERp1; pituitary adenylate cyclase activating polypeptide; pituitary adenylate cyclase activating polypeptide 1; Pituitary adenylate cyclase-activating polypeptide; Pituitary adenylate cyclase-activating polypeptide 27; Pituitary adenylate cyclase-activating polypeptide 38; pituitary adenylate cyclase-activating polypeptide precursor (Pacap); prepro-PACAP; PRP-48
Gene Aliases: ADCYAP1; PACAP
UniProt ID: (Human) P18509, (Rat) P13589
Entrez Gene ID: (Human) 116, (Rat) 24166
Molecular Function: neuropeptide
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