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|Tested species reactivity||Human, Rat|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Synthetic peptide derived from the C-terminal region of the human, mouse, and rat PACAP protein|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
ADCYAP1 is adenylate cyclase activating polypeptide 1. Mediated by adenylate cyclase activating polypeptide 1 receptors, this polypeptide stimulates adenylate cyclase and subsequently increases the cAMP level in target cells. Adenylate cyclase activating polypeptide 1 is not only a hypophysiotropic hormone, but also functions as a neurotransmitter and neuromodulator. In addition, it plays a role in paracrine and autocrine regulation of certain types of cells. This gene encodes three different mature peptides, including two isotypes, a shorter form and a longer form.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
ADCYAP1; adenylate cyclase activating polypeptide 1 (pituitary); PACAP; pituitary adenylate cyclase activating polypeptide; pituitary adenylate cyclase activating polypeptide 1; Pituitary adenylate cyclase-activating polypeptide; pituitary adenylate cyclase-activating polypeptide precursor (Pacap); prepro-PACAP