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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues A(167) I V E A L N G K E V A A Q V K A P L V L K D(189) of human PARK7.|
|Purification||Antigen affinity chromatography|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||Assay dependent|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-4369 detects PARK7 from human and mouse samples.
PA1-4369 has been successfully used in Western blot and immunohistochemistry procedures.
The PA1-4369 immunizing peptide corresponds to amino acid residues 167-189 from human PARK7.
Four chromosomal loci (PARK2, PARK6, PARK7, and PARK9) associated with autosomal recessive, early onset parkinsonism are known. Positional cloning within the refined PARK7 critical region recently identified mutations in the DJ-1 gene in PARK7-linked families. Mutations in the PARK7/DJ-1 gene cause autosomal-recessive Parkinsons disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
DJ-1; epididymis secretory sperm binding protein Li 67p; Oncogene DJ1; Parkinson disease (autosomal recessive, early onset) 7; Parkinson disease protein 7; Parkinson disease protein 7 homolog; parkinson protein 7; Protein deglycase DJ-1; protein DJ-1; RNA-binding protein regulatory subunit
DJ-1; DJ1; HEL-S-67p; PARK7