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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||His-tagged recombinant protein comprised of the C-terminal 261 residues of LRRK2.|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:100-1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
augmented in rheumatoid arthritis 17; Leucine-rich repeat (LRR) kinase 2; Leucine-rich repeat kinase 2; leucine-rich repeat serine/threonine-protein kinase 2; Park8
4921513O20Rik; 9330188B09Rik; AURA17; AW561911; cI-46; D630001M17Rik; DARDARIN; Gm927; LRRK2; PARK8; RIPK7; ROCO2