Fabgennix

PAX3 Polyclonal Antibody, Biotin

Product Details

PAX3-BIOTIN

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:1,000	-
ELISA (ELISA)	1:10,000	-
Immunoprecipitation (IP)	1:50-1:250	-

Product Specifications
Species Reactivity	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Synthetic peptide corresponding to unique amino acid sequence on PAX3 protein.
Conjugate	Biotin
Form	Liquid
Concentration	0.5-1.5 mg/mL
Purification	Affinity chromatography
Storage buffer	proprietary buffer, pH 7.4-7.8, with 0.5% BSA, 30% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Target Information

Pax 3 (Paired Box 3) is a transcription factor that is involved in development of the peripheral nervous system, melanocytes, some vascular smooth muscle, and a number of other derivatives. It regulates neurogenesis in pre-migratory neural crest cells from the dorsal neural tube, and in myogenic progenitors in the presomitic mesoderm and the hypaxial somites. Alternative splicing results in isoforms having different C-termini.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: HuP2; MGC120381; MGC120382; MGC120383; MGC120384; MGC134778; paired box homeotic gene 3; Paired box protein Pax-3; paired domain gene 3; paired domain gene HuP2

Gene Aliases: CDHS; HUP2; PAX3; WS1; WS3

UniProt ID: (Human) P23760

Entrez Gene ID: (Human) 5077

Function(s)

transcription from RNA polymerase II promoter apoptotic process nervous system development muscle organ development sensory perception of sound organ morphogenesis neural crest formation positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter

Process(es)

transcription factor activity, sequence-specific DNA binding protein binding sequence-specific DNA binding HMG box domain binding