Active Motif

PAX7 Monoclonal Antibody (2F12H4)

View all (20) PAX7 antibodies

Questions & Answers

Questions & Answers

Product Details

39803

Applications	Tested Dilution	Publications
Western Blot (WB)	Assay-dependent	-
Immunocytochemistry (ICC/IF)	Assay-dependent	-

Product Specifications
Species Reactivity	Mouse
Host/Isotype	Rat / IgG2b
Class	Monoclonal
Type	Antibody
Clone	2F12H4
Immunogen	This PAX7 antibody was raised against a peptide derived from mouse PAX7.
Conjugate	Unconjugated
Form	Liquid
Concentration	1 mg/mL
Purification	Protein G
Storage buffer	70mM tris, pH 8, with 30% glycerol, 0.07mM EDTA, 105mM NaCl, 31mM glycine
Contains	0.035% sodium azide
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles
RRID	AB_2793348

Target Information

This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: FLJ37460; paired box gene 7; Paired box protein Pax-7; paired box transcription factor PAX7; PAX7A

Gene Aliases: Pax-7; Pax7

UniProt ID: (Mouse) P47239

Entrez Gene ID: (Mouse) 18509

chromatin remodeling transcription, DNA-templated regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter transcription from RNA polymerase II promoter multicellular organism development muscle organ development skeletal muscle tissue development organ morphogenesis regulation of cell fate commitment regulation of gene expression skeletal muscle satellite cell commitment spinal cord association neuron differentiation dorsal/ventral neural tube patterning positive regulation of histone methylation regulation of protein binding skeletal muscle tissue regeneration positive regulation of transcription from RNA polymerase II promoter neuron fate commitment embryonic skeletal system development cartilage development muscle tissue morphogenesis positive regulation of myoblast proliferation

Process(es)

transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding protein binding sequence-specific DNA binding