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PAX7 Antibody (MA5-35445) in WB
Western blot analysis of PAX7 in extracts of various cell lines. Samples were incubated with PAX7 Monoclonal antibody (Product # MA5-35445) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 3 min.
Product Details
MA5-35445
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
ARC0914
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human PAX7 (P23759)
Conjugate
Form
Liquid
Concentration
1.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2849346
Product Specific Information
Immunogen sequence: SAYGARHSFS SYSDSFMNPA APSNHMNPVS NGLSPQVMSI LGNPSAVPPQ PQADFSISPL HGGLDSATSI SASCSQRADS IKPGDSLPTS QAYCPPTYST T
Target Information
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ37460; HuP1; paired box gene 7; paired box homeotic gene 7; Paired box protein Pax-7; paired box transcription factor PAX7; paired domain gene 7; PAX7 transcriptional factor; PAX7A
Gene Aliases: HUP1; Pax-7; PAX7; PAX7B; RGD1564360; RMS2
UniProt ID: (Human) P23759, (Mouse) P47239
Entrez Gene ID: (Human) 5081, (Mouse) 18509, (Rat) 500574
chromatin remodeling
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
multicellular organism development
muscle organ development
skeletal muscle tissue development
organ morphogenesis
regulation of cell fate commitment
regulation of gene expression
skeletal muscle satellite cell commitment
spinal cord association neuron differentiation
dorsal/ventral neural tube patterning
positive regulation of histone methylation
regulation of protein binding
skeletal muscle tissue regeneration
positive regulation of transcription from RNA polymerase II promoter
neuron fate commitment
embryonic skeletal system development
cartilage development
muscle tissue morphogenesis
positive regulation of myoblast proliferation
anatomical structure morphogenesis
negative regulation of apoptotic process
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