Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
PA1-27525 detects PCOLN3 from human samples.
PA1-27525 may be successfully used in Western blot applications. By Western blot, this antibody has only been tested on fusion protein.
The PA1-27501 immunogen is a synthetic peptide corresponding to human Charged multivesicular body protein 1a.
This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Bf; C3 Proaccelerator; cfb; Complement factor P; H2-Bf; Properdin; properdin P factor, complement
Gene Aliases: CFP; PFC
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