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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 230 and 290 of CD274|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Contains||0.025% Proclin 300|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28115 targets CD274 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-28115 immunogen is a synthetic peptide corresponding to a region within amino acids 230 and 290 of CD274.
Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
B7 homolog 1; B7-H; B7H1; CD274 antigen; PDCD1 ligand 1; PDCD1L1; PDCD1LG1; PDL1; programmed cell death 1 ligand 1; programmed death ligand 1
B7-H; B7H1; CD274; PD-L1; PDCD1L1; PDCD1LG1; PDL1