Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:4,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50 | - |
Immunocytochemistry (ICC/IF) |
1:100 | - |
Flow Cytometry (Flow) |
1:100 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
OTI6B6 |
Immunogen |
Full length human recombinant protein of PDE4A produced in HEK293T cell |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Affinity Chromatography |
Storage buffer |
PBS, pH 7.3, with 1% BSA, 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2724970 |
Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. Cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. PDE4A is a class IV cAMP-specific PDE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cAMP-specific 3',5'-cyclic phosphodiesterase 4A; DPDE2; PDE46; phosphodiesterase 4A, cAMP-specific (dunce; phosphodiesterase E2 dunce homolog, Drosophila; phosphodiesterase isozyme 4
Gene Aliases: DPDE2; PDE4; PDE46; PDE4A
UniProt ID: (Human) P27815
Entrez Gene ID: (Human) 5141
Molecular Function:
phosphodiesterase
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