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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||N-terminal peptide unique to PDE4B3 subtype variants.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 20% glycerol|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-31138 detects PDE4B3 from mouse, human, rat samples. PA1-31138 does not cross react with PDE4B1, PDE4B2 and PDE4B4 nor with PDE4A, PDE4C or PDE4D.
PA1-31138 has been successfully used in Western blot applications. Predicted molecular weight: 100 kDa.
The PA1-31138 immunogen is a N-terminal peptide unique to PDE4B3 subtype variants.
Enzymes of the cAMP-dependent phosphodiesterase type 4 (PDE4) family are important in hydrolyzing cAMP produced by G-protein coupled receptor (GPCR) stimulated adenylyl cyclases. Four genes (PDE4A, B, C and D) make up the PDE4 family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
3',5'-cyclic AMP phosphodiesterase; cAMP-specific 3',5'-cyclic phosphodiesterase 4B; DPDE4; dunce-like phosphodiesterase E4; MGC93193; PDE4/IVb; Pde4B1; Pde4B2; Pde4B3; Pde4B4; Phosphodiesterase 4B cAMP-specific (dunce; Phosphodiesterase 4B, cAMP-specific (dunce; phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)
DPDE4; dunce; PDE4/IVb; PDE4B; Pde4B1; Pde4B2; Pde4B3; Pde4B4; PDEIVB; R74983