Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 8
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
PrBP/delta, previously known as PDE6/delta, is the effector enzyme in the G protein-mediated signal transduction cascade in the visual system. There are five different subunits consisting of rod and cone specific catalytic subunits: alpha (Cone), alpha (Rod), and beta (Rod), the inhibitory subunit gamma, and subunit delta of unknown function (which likely interacts with many other proteins besides the PDE6 family). PRBP/delta has been implicated in the transport and membrane targeting of prenylated proteins (including PDE6) from their site of synthesis in the inner segment to their final destination in the outer segment of rods and cones (Norton et. al., 2005).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cGMP-phosphodiesterase delta subunit; GMP-PDE delta; PDE6D; pde6D gene for cGMP-phosphodiesterase delta subunit; phosphodiesterase 6D, cGMP-specific, rod, delta; Protein p17; Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
Gene Aliases: AI841218; JBTS22; PDE6D; PDED; PrBP/delta; zgc:92605
UniProt ID: (Dog) Q9XT54, (Human) O43924, (Mouse) O55057
Entrez Gene ID: (Dog) 403781, (Human) 5147, (Rat) 363272, (Mouse) 18582, (Zebrafish) 436981
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support