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|Tested species reactivity||Human, Mouse, Rat|
|Published species reactivity||Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||GST fusion protein containing a carboxy-terminal fragment of human PDGF receptor ß|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
|Contains||<0.02% sodium azide|
|Tested Applications||Dilution *|
|Immunohistochemistry (Frozen) (IHC (F))||1:100|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunocytochemistry (ICC)||See 2 publications below|
It is not recommended to aliquot this antibody.
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bile acids induce hepatic differentiation of mesenchymal stem cells.
MA5-15143 was used in immunocytochemistry to study the effect of bile acids on mesenchymal stem cells in liver
|Sawitza I,Kordes C,Götze S,Herebian D,Häussinger D||Scientific reports (5:null)||2015|
Hepatic stellate cells support hematopoiesis and are liver-resident mesenchymal stem cells.
MA5-15143 was used in immunocytochemistry to study the role of hepatic stellate cells as liver-resident mesenchymal stem cells and their role in hematopoiesis
|Kordes C,Sawitza I,Götze S,Häussinger D||Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology (31:290)||2013|
Beta platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140b; JTK12; PDGF beta chain; PDGF Receptor beta; PDGF-R-beta; PDGFR; PDGFR-1; PDGFR-beta; PDGFR1; Platelet-derived growth factor receptor 1; Platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide
AI528809; CD140B; IBGC4; IMF1; JTK12; KOGS; PDGFR; PDGFR-1; PDGFR1; PDGFRB; PENTT