|Tested species reactivity||Yeast|
|Published species reactivity||Not Applicable|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Yeast nuclear preparation.|
|Storage buffer||tissue culture supernatant|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:10,000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
MA1-10032 detects PDI1P from S. cerevisiae samples.
Pdi1p is a yeast protein disulfide isomerase. It is a major endoplasmic reticulum protein with chaperone and co-chaperone activity, involved in retention of resident ER proteins. It also has a role in recognizing proteins targeted for ER-associated degradation (ERAD) and is a member of the protein disulfide isomerase family. Proteins in this family also can break disulfide bonds on substrate proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
A Complex of Htm1 and the Oxidoreductase Pdi1 Accelerates Degradation of Misfolded Glycoproteins.
MA1-10032 was used in western blot to study acceleration of degradation of misfolded glycoproteins by a complex of Htm1 and the oxidoreductase Pdi1
|Pfeiffer A,Stephanowitz H,Krause E,Volkwein C,Hirsch C,Jarosch E,Sommer T||The Journal of biological chemistry (291:12195)||2016|