|Tested species reactivity||Human, Mouse, Rat|
|Published species reactivity||Rat, Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide made to the C-terminus of mouse PDZK2 / IKEPP.|
|Storage buffer||whole serum|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 2 publications below|
This antibody is not recommended for ICC/IF applications.
Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Shank2 redistributes with NaPilla during regulated endocytosis.
PA3-16819 was used in western blot to study the role of Shank2 in regulating the sodium-phosphate co-transporter IIa.
|Dobrinskikh E,Giral H,Caldas YA,Levi M,Doctor RB||American journal of physiology. Cell physiology (299:C1324)||2010|
Intestinal anion exchanger down-regulated in adenoma (DRA) is inhibited by intracellular calcium.
PA3-16819 was used in western blot to investigate the role of PDZK1 in calcium-mediated inhibition of colonic NaCl absorption
|Lamprecht G,Hsieh CJ,Lissner S,Nold L,Heil A,Gaco V,Schäfer J,Turner JR,Gregor M||The Journal of biological chemistry (284:19744)||2009|